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DAPT helps secondary prevention after minor strokes

HOUSTON, TX (May16, 2018)

Adding clopidogrel (Plavix) to aspirin therapy in the immediate days following a minor stroke prevented more ischemic events, but at the cost of increased bleeding risk, a randomized trial suggested. The CHANCE trial used a lower loading dose of clopidogrel, but this is an unlikely explanation for the difference, since most bleeding events in the POINT trial occurred long after the loading dose," James Grotta, M.D., of Memorial Hermann Hospital in Houston, noted in an accompanying editorial.
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