A recent study led by McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth) and funded by the NIH showed that cardiac arrest patients resuscitated by paramedics using laryngeal tube insertion versus endotracheal intubation were more likely to survive. Results were published in the August 28, 2018, issue of JAMA, in an NIH press release and in a McGovern Medical School article.
“This is one of the first randomized trials to show that a paramedic airway intervention can improve cardiac arrest survival,” said lead author Henry E. Wang, MD, MS, professor and vice chair for research in the department of Emergency Medicine at McGovern Medical School. “Based upon these results, use of the newer, more flexible tube could result in thousands of saved lives every year,” says Dr. Wang.
Funded by the National Heart, Lung and Blood Institute (NHLBI), the study is the largest of its kind to test oxygen delivery methods used by firefighters, emergency medical technicians and paramedics.
Dr. Wang describes the study as a multicenter head-to-head comparison between the newer intubation tube and a traditional one. The study was conducted by the Resuscitation Outcomes Consortium research network and included the Birmingham, Dallas-Fort Worth, Milwaukee, Pittsburgh and Portland communities.
“For over three decades, emergency medical services personnel in the U.S. have performed intubation to deliver oxygen into the lungs of cardiac arrest victims. While identical to techniques used by doctors in the hospital, intubation in the prehospital setting is very difficult and fraught with errors,” says Dr. Wang. “Our trial showed that cardiac arrest patients treated using the newer and easier laryngeal tube device may have a higher survival rate.”
Sudden cardiac arrest, or loss of mechanical activity of the heart, is usually caused by a heart attack. More than 400,000 individuals are treated for out-of-hospital cardiac arrest each year, with the vast majority occurring at home, according to the American Heart Association. Studies show that only about 10 percent of people who suffer cardiac arrest outside the hospital survive. Delivery of oxygen to the lungs is a critical part of reviving a patient from cardiac arrest.
The research study – Pragmatic Airway Resuscitation Trial (PART) – compared survival rates among 3,000 adults with cardiac arrest treated by paramedic crews from 27 emergency medical services (EMS) agencies from December 2015 to November 2016. Approximately half received the newer laryngeal tube airway management, while the other half received traditional endotracheal intubation.
Overall, survival was higher in the new tube device group than in the standard intubation group. With the new tube, 18.3 percent survived three days in the hospital, while in the intubation group, 15.4 percent survived three days. A total of 10.8 percent in the new tube group survived to leave the hospital, while 8.1 percent in the intubation group survived to leave the hospital. The proportion of patients surviving with good brain function was also higher for the new device than standard intubation.
While additional research is needed to support the study’s findings, the researchers believe that the benefits of the newer airway device are due to its easier technique, leading to better blood flow and oxygen delivery. They are continuing to analyze the data to gain additional insight into the study results.
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